The Non-Neuronal Cholinergic System in Health and Disease
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چکیده
منابع مشابه
The non-neuronal cholinergic system in health and disease.
Acetylcholine (ACh) is not only a neurotransmitter but is an ancient molecule that can be released by and act on non-neuronal cells. In these cells the system of ACh-synthesizing enzymes, transporters, receptors and degrading enzymes is termed the non-neuronal cholinergic system (NNCS). There is increasing evidence that the NNCS is dysregulated in various diseases and can have an influence on t...
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Acetylcholine, a prime example of a neurotransmitter, has been detected in bacteria, algae, protozoa, and primitive plants, indicating an extremely early appearance in the evolutionary process (about 3 billion years). In humans, acetylcholine and/or the synthesizing enzyme, choline acetyltransferase (ChAT), have been found in epithelial cells (airways, alimentary tract, urogenital tract, epider...
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ژورنال
عنوان ژورنال: Pharmacology
سال: 2013
ISSN: 1423-0313,0031-7012
DOI: 10.1159/000355835